The application of genetic editing techniques for the prevention or cure of disease is a highly promising tool for the future of humanity. However, its implementation contains a number of ethical and legal challenges that should not be underestimated. On this basis, some sectors have already asked for a veto on any intervention that modifies the human germ line, while supporting somatic line editing. In this paper, I will support that this suggestion makes no sense at all, because the somatic/germ (...) line disjunctive has no moral relevance and, therefore, it should not play any role in legal terms. I will provide a number of reasons to hold this assumption, such as the non‐sacred nature of the germ line, the difference between germ line and human genome modification, or the moral importance of the presence of a will to create modified descendants. While doing so, I will provide some examples of the different approaches to germ line editing adopted by different regulations so as to demonstrate that, contrary to what is sometimes stated, a general ban on this practice is not the rule, but the exception. Additionally, I will show how alternative options which currently exist, such as a selective ban based on criteria different to the germ line/somatic line distinction, match better with the need to conciliate research needs and legitimate ethical concerns. Finally, I will introduce some further suggestions to this same purpose. (shrink)

The aim of the present paper is to reinforce some of the affirmations made by Vera Lucia Raposo in a recent paper published by the Journal of Bioethical Inquiry. According to her, germline gene editing does not violate human dignity at all. This article offers some complementary ideas supporting her statement. In particular, four main arguments are stressed. Firstly, not only is the idea of human dignity unclear, but the idea of the human genome suffers from a general lack of (...) concreteness, which has dramatic consequences for the debate. Secondly, it is highlighted that if we believe that the immutability of the human genome underpins human dignity, then it should be our duty to use the tools of genetic modification to reverse any accidental changes that occur in nature. Thirdly, it is showed that if the alteration of germline constitutes an attack on human dignity, then we should also refrain from performing medical practices such as chemotherapy, which cause precisely this effect. Finally, we argue that modification of germline is not contrary to human dignity but an excellent expression of our autonomy. (shrink)

Human germline gene editing constitutes an extremely promising technology; at the same time, however, it raises remarkable ethical, legal, and social issues. Although many of these issues have been largely explored by the academic literature, there are gender issues embedded in the process that have not received the attention they deserve. This paper examines ways in which this new tool necessarily affects males and females differently—both in rewards and perils. The authors conclude that there is an urgent need to include (...) these gender issues in the current debate, before giving a green light to this new technology. (shrink)

La aparición de las modernas técnicas de modificación genética (CRISPRCas9) ha abierto maravillosas expectativas en el campo de la biomedicina. Sin embargo, su aplicación sobre la línea germinal humana despierta todavía una fuerte oposición por parte de amplios colectivos. A menudo se aduce que factores como el riesgo que implica esta técnica, su propia futilidad, la amenaza implícita a la integridad del genoma humano, o la posibilidad de que acaben dando naturaleza a una nueva eugenesia justifican la necesidad de trazar (...) una prohibición o, al menos, una moratoria sobre ellas. En este texto debatiremos la solvencia de cada uno de estos argumentos, concluyendo que, en realidad, no hay buenos motivos para oponerse a la técnica que nos ocupa. (shrink)

El edificio Rana Plaza, en Bangladesh, se vino abajo en Abril 2013. Como consecuencia, más de mil personas perdieron la vida. Este suceso despertó inmediatamente una fuerte crítica a la actuación de las grandes corporaciones trasnacionales. Se les acusó de no haber hecho todo lo que podían para mejorar las condiciones laborales en ese país, a pesar de que su poder de compra les permitía dictar las reglas. Este artículo pretende explorar la legitimidad de esa acusación. Con tal fin, se (...) explorará la responsabilidad moral de la situación existente en muchos países en vías de desarrollo. Ese análisis desvelará que, más allá de las citadas corporaciones, es posible hablar de responsabilidades en el caso de muchos de nosotros. Nuestra doble vertiente de ciudadanos y consumidores/inversores nos dota de un poder que implica también una responsabilidad. (shrink)

The discussion about the animal rights is becoming nowadays one of the most important ones in the fields of philosophy or laws. Authors such us Singer, Regan, or, in the Latin countries, Riechmann, de Lora, Horta or Mostrerin talk about our moral duty to recognize to some animals the same rights we recognize to the human beings. The Great Ape Project has been even discussed in some of our Parliaments. However, “traditional” philosophers and lawyers do not seem to have in (...) mind any answers to these challenges. The purpose of this paper is to face this fact, arguing why we are not obligated to consider animal rights. (shrink)

El objetivo de este texto consiste en analizar las consecuencias que la creación de quimeras e híbridos puede llegar a tener sobre los paradigmas éticos con los que contamos ahora mismo, especialmente el antropocentrismo. Intentaremos demostrar que este paradigma no es capaz de afrontar adecuadamente la existencia de esta clase de seres, que desafían las premisas sobre las que se construye. Esto debería llevarnos a reemplazarlo por otros modelos éticos.

En un mundo globalizado, el consumidor posee un poder superior al que nunca ha tenido. La amplitud de los mercados hace que le sea muy sencillo sustituir unos bienes por otros a la hora de satisfacer una necesidad. Sus decisiones de compra son, a su vez, las que deciden qué empresas triunfarán y cuáles no. De ahí que sea cada vez más cabal hablar de soberanía del consumidor. La conciencia de este poder es esencial, ya que permite pensar en formas (...) de poner límites al libre mercado basadas en la idea de justicia. Ahora bien, esto sólo será posible a través de acciones concertadas, que utilicen herramientas eficaces, como el boicot de compra. Este texto analiza las posibilidades con las que cuenta el consumidor para ejercer su poder adecuadamente. (shrink)

Potential applications of genome editing in assisted reproductive technology (ART) raise a vast array of strong opinions, emotional reactions and divergent perceptions. Acknowledging the need for caution and respecting such reactions, we observe that at least some are based on either a misunderstanding of the science or misconceptions about the content and flexibility of the existing legal frameworks. Combining medical, legal and ethical expertise, we present and discuss regulatory responses at the national, European and international levels. The discussion has an (...) EU starting point and is meant as a contribution to the general international regulatory debate. Overall, this paper concludes that gene editing technologies should not be regulated autonomously. Rather, potential uses should be regulated under general, existing frameworks and where applicable by reference to sufficiently equivalent technologies and techniques already subject to specific regulation. To be clear, we do not argue for the hasty introduction of gene editing as a reproductive treatment option in the immediate future. We call for caution with regard to overreaching moratoria and prohibitions that will also affect basic research. We recommend flexible regulations that allow for further responsible research into the potential development of the technology. We call for an open and inclusive debate and argue that scientific communication should claim a more prominent role to counter the danger of widespread misinformation. A high level of transparency and accuracy should guide scientific communication while simultaneously global‐scale responsibility and governance should be fostered by promoting cross‐disciplinary thinking and multi‐level stakeholder involvement in legal and regulatory processes. (shrink)